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5 Signs Your Centrifuge Needs Maintenance or Replacement

Updated On 11/28/2025

5 Signs Your Centrifuge Needs Maintenance or Replacement

A centrifuge is one of the hardest-working instruments in the lab. It spins samples thousands of times per minute, handles constant imbalance checks, manages heat, and delivers the separations your workflow depends on. When it’s performing well, you barely notice it. But when something goes wrong, your entire lab feels it.

From inaccurate separations to unexpected downtime, a failing centrifuge can quietly erode productivity long before it stops working altogether. That’s why recognising the early signs of wear is essential—not just for safety, but for data integrity and operational continuity.

Below are the five clearest indicators that your centrifuge is ready for maintenance… or might be approaching the end of its service life.

 

1. It Suddenly Sounds Different

A healthy centrifuge has a sound you learn to trust. When that sound changes, you should pay attention.

If you start noticing:

  • A louder humming

  • Metallic scraping

  • Vibrations that travel through the bench

  • A rhythmic thumping

  • High-pitched whining

…it’s more than just “background noise.”

What’s actually happening?

These sounds often signal worn bearings, loose components, a misaligned drive shaft, or early rotor imbalance. If left unchecked, minor vibration can escalate into a serious safety issue. In extreme cases, rotor failure is catastrophic.

If your centrifuge sounds different today than it did last week, it’s time to investigate.

 

2. Your Samples Aren’t Separating Like They Used To

This is one of the most overlooked warning signs.

If your pellets are softer, smeared, incomplete, or inconsistent between runs, don’t blame your technique just yet. A centrifuge that fails to reach or maintain its programmed RCF can produce unreliable separations.

Typical causes include:

  • Calibration drift

  • Sensor malfunction

  • A weakening motor

  • Rotor slippage

  • Internal electronics aging

For research labs, diagnostics labs, and accredited testing facilities, this isn’t just inconvenient—it’s a compliance risk.

 

3. The Rotor Shows Wear, Corrosion, or Cracks

Your rotor is the heart of your centrifuge, and also its greatest point of risk. Every run applies intense stress, and even microscopic defects can grow silently.

Red flags include:

  • Corrosion spots

  • Surface pitting

  • Hairline cracks

  • Dull or uneven finish

  • Distortion around the rotor hub

Most rotor failures are traced back to unnoticed damage. If your rotor shows visible wear, remove it from service immediately. Depending on its age and availability of replacement parts, this may be the moment to consider replacing the entire unit.

 

4. Cooling Isn’t Performing Like It Used To

Refrigerated centrifuges are crucial for biological, enzymatic, or temperature-sensitive workflows.
When cooling becomes unreliable, results can suffer long before an alarm appears.

Warning signs:

  • Slower cooling times

  • Temperature overshoot

  • The chamber warming mid-run

  • Compressor running too loudly

  • Temperature error messages

A failing refrigeration system is often expensive to repair, especially on ageing instruments. For many labs, upgrading is more cost-effective than restoring a failing cooling unit.

 

5. Persistent Error Codes or Unexpected Shutdowns

Modern centrifuges are filled with sensors—speed, imbalance, temperature, lid lock, rotor recognition, chamber stability.
These systems protect your samples and your staff.

But when an instrument begins:

  • Displaying random error messages

  • Failing to recognise rotors

  • Tripping imbalance warnings

  • Stalling mid-program

  • Rebooting without cause

…it’s a sign that internal electronics or control boards are failing.

Once reliability becomes unpredictable, trust becomes the bigger issue—not just repair cost.

 

Repair or Replace? How to Make the Right Call

Not every issue means the centrifuge is at the end of its life. But there are clear thresholds.

A repair makes sense when:

  • The centrifuge is under 8 years old

  • The rotor and chamber look healthy

  • Parts are readily available

  • Issues relate to simple sensors, seals, or calibration

Replacement is usually the better option when:

  • The centrifuge is older than 10–12 years

  • Rotor wear or corrosion is visible

  • Cooling systems keep failing

  • Errors occur frequently despite servicing

  • Spare parts are no longer supplied

  • Workflow uptime is regularly affected

Labs in accredited or high-throughput environments often adopt a proactive upgrade cycle to protect efficiency and data integrity.

 

Reliable Brands for Long-Term Performance

When replacement becomes the smarter choice, many Australian labs turn to trusted global manufacturers known for precision and service continuity:

  • Eppendorf

  • Thermo Scientific

  • Hettich

  • Hermle

  • Benchmark Scientific

  • Ohaus

  • LLG Labware

These brands offer reliable performance across clinical, research, educational, and industrial settings—and are all available through LabFriend.

 

Conclusion

A centrifuge doesn’t fail overnight— it sends early signals. Noise, vibration, inconsistent separations, rotor wear, temperature drift, and error messages all point to internal stress long before a complete breakdown.

By recognising these signs early, labs can protect their samples, minimise downtime, and avoid costly emergencies. Whether your centrifuge needs a quick calibration or a full upgrade, taking action now ensures your lab stays productive and safe.

If your centrifuge is showing signs of wear or you’re exploring upgrade options, LabFriend offers an extensive range from Eppendorf, Thermo Scientific, Hettich, Hermle, Benchmark Scientific, Ohaus, and LLG Labware. Our team can help you select the right model for your workflow and budget.

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